CD4 T cells inhibit the CD8 T cell response during low-dose virus infection.

سطح بالای پاسخ ایمنی اختصاصی لنفوسیت‌های CD4+وCD8+ نسبت به سیتومگالوویروس و همبستگی بین آن‌ها در بیماران مبتلا به لوسمی لنفوسیتی مزمن سلولB

  High level of CMV-specific CD4+ and CD8+cells Immune Response and Correlation Between them in B-cell Chronic Lymphocytic Leukemia Patients     B. Pourgheysri [1] , P. Moss [2]     Received: 10/09/07 Sent for Revision: 05/03/08 Received Revised Manuscript: 06/12/08 Accepted: 30/12/08   Background and Objective: Chronic lymphocytic leukemia (CLL) is characterized by a monoclonal proliferation o...

Diversity of Trends of Viremia and T-Cell Markers in Experimental Acute Feline Immunodeficiency Virus Infection

OBJECTIVE The early events of human immunodeficiency virus infection seem critical for progression toward disease and antiretroviral therapy initiation. We wanted to clarify some still unknown prognostic relationships between inoculum size and changes in various immunological and virological markers. Feline immunodeficiency virus infection could be a helpful model. METHODS Viremia and T-cell ...

P 130: The Role of Host T- Cell Lymphocyte in Immunopathogenesis of HTLV-I-Associated Myelopathy/Tropical Spastic Paraparesis

Human T-cell lymphotropic virus type 1 (HTLV-1) is associated with adult T-cell leukemia/lymphoma (ATL) and HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). Only a limited percentage of infected individuals develop disease in response to the virus while the majority remain asymptomatic and HAM/TSP is the most common clinical manifestation of the virus. HAM/TSP is an inflamma...

CD4 T cells are required for CD8 T cell survival during both primary and memory recall responses.

The role of CD4 T cell help in primary and secondary CD8 T cell responses to infectious pathogens remains incompletely defined. The primary CD8 T response to infections was initially thought to be largely independent of CD4 T cells, but it is not clear why some primary, pathogen-specific CD8 T cell responses are CD4 T cell dependent. Furthermore, although the generation of functional memory CD8...

Ratio of CD4+ to CD8+ T-Cells in the Recent Reported Cases of Bird Flu Infection in Asia